PROVIDENCE, July 28, 2005 (LifeSiteNews.com) - Even while the US Food and Drug Administration (FDA) is investigating deaths related to it, the manufacturers of the drug Mifepristone continue to deny that their drug was the cause of the bacterial infection that has killed five women.

Now, however, Professor Ralph P. Miech, a professor emeritus in the Department of Molecular Pharmacology, Physiology, and Biotechnology at Brown University, has provided clear evidence that the drug causes conditions in which bacterial infections can take hold and become deadly. The Annals of Pharmacotherapy will publish Dr. Miech’s study in the September issue.

During an abortion using Mifepristone, the first stage of the drug shuts off progesterone, which halts the flow of nutrition to the placenta and the child. The second stage drug causes contractions that expel the dead child.

Dr. Miech shows that the anti-progesterone effects of Mifepristone also cause changes in the cervix that allow C. sordellii, a common vaginal bacteria, to enter the cervical canal. C. sordellii thrives in this low-oxygen environment and derives nutrition from the decaying fetal tissue.

Mifepristone, Miech says, also disrupts the immune system, which “impairs the body’s ability to fight off C. sordellii and may help spread the bacteria’s toxic by-products, a combination that sometimes results in widespread septic shock.” The resulting infection makes its way into the blood stream, becoming life threatening. The danger of the drug is increased because of a lack of the usual symptoms of infection such as fever.

Earlier this month the FDA announced that it would be investigating the serious adverse effects of Mifepristone (trade name Mifeprex, also known as RU-486) the drug recommended by many abortionists and abortion lobbyists as an at-home abortion kit. On July 19, the FDA issued a public health advisory on the risk of sepsis or blood infection when undergoing abortion using Mifeprex.

On the same day the FDA issued its advisory, the drug’s manufacturer, Danco Laboratories, admitted that five deaths had occurred in women while using Mifeprex for abortion but denied that the drug was the cause. “No causal relationship between these events and the use of Mifeprex and Misoprostol has been established,” claimed Danco Labs Medical Director Richard Hausknecht, M.D., in a release.

Miech’s findings are consistent with those of Frank Gentle, the supervising coroner in the case of Holly Patterson, the California teen who, Gentle said, died from septic shock after using Mifeprex abortion drugs.

The pro-family organization, Concerned Women for America, also reports that information it received under the Freedom of Information Act shows that out of approximately 600 case studies, the abortion drug caused 220 cases of hemorrhage that were either life-threatening or extremely serious.

Read the abstract of Dr. Miech’s work in the Annals of Pharmacotherapy
http://www.theannals.com/cgi/content/abstract/aph.1G189v1

Read previous LifeSiteNews.com coverage:
  Abortion Drug RU-486 Company Admits to Death of Five Women
http://www.lifesite.net/ldn/2005/jul/05071905.html

FDA Issues Public Health Advisory for Abortion Drug RU-486 - 4 Deaths in Less than 2 Years
http://www.lifesite.net/ldn/2005/jul/05072003.html

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