CHICAGO, July 22, 2004 ( – In-vitro fertilization involves a process known as ovulation induction, where a woman is placed on drugs that promote the formation of several eggs. A new study published in the Journal of Periodontology reveals that the drugs used are leading to increased incidence of gingivitis, a condition of inflammation of the gums, leading to bleeding and painful gums.  Whereas a woman normally releases only one egg during ovulation at a time, ovulation-inducing drugs such as the most common, clomiphene citrate, causes a woman’s ovaries to produce multiple eggs.

The drug is not without its dangers, as the research points out. Whether alone or in combination with other hormones, clomiphene “exacerbates gingival inflammation [and] bleeding . . . the duration of the usage of these drugs is strongly associated with the severity of gingival inflammation.”  See related coverage:  Frozen Embryos Linked to Ectopic Pregnancy Medical Journal Reports Dangers of IVF   tv