Hilary White

Obama admin’s FDA mulling three-parent embryo creation

Hilary White
Hilary White
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WASHINGTON, D.C., October 31, 2013 (LifeSiteNews.com) – While some European ethicists and politicians have called for an end to the creation of “three-parent” IVF embryos, the U.S. Food and Drug Administration has announced it is considering allowing the practice - without having held a public consultation.

Researchers say that the technique “modifies standard IVF technology” to create an embryo from the eggs of two women and sperm from one man.

The FDA’s most recent draft guidance on the issue included no mention of the ethical concerns over the nature of the procedure itself, but only offers suggestions for developing early stage clinical trials.

“This guidance is intended to facilitate [cellular and gene therapy] development by providing recommendations regarding selected aspects of the design of early-phase clinical trials of these products,” the document said.

The FDA’s Cellular, Tissue and Gene Therapies Advisory Committee had planned on holding a public consultation in Silver Spring, Maryland, on October 22-23, but an announcement said they had postponed it because of the federal government shutdown.

No new consultation date has been announced.

Among those objecting to the FDA’s proposal is the Arkansas-based Family Council, who have published their response to the consultation, listing three reasons the creation of children with three genetic parents should not be allowed.

First, they said, the technique, like human embryonic stem cell research, inevitably involves the creation of human embryos whose sole purpose is to be “created and killed in the name of science.”

They also said that the research, while it is purported to be about preventing genetic disorders, “could also be used by polygamous or polyamorous ‘families’ to ‘create’ children biologically-related to all the adults involved in the relationship.”

The document also warns of potentially wide-ranging issues in law and public policy related to child welfare or parental rights, all of which currently “assumes children have two biological parents.”

“While it’s fairly common for children to be reared by only one parent, or for someone other than a biological parent to have custody of a child, it is not known what damage could be done to the rights of two-parent children if the laws change to accommodate parents of three-parent children,” the group said.

The Vatican is on record against the procedure. The document, Dignitas Personae, by the Congregation for the Doctrine of the Faith, says that, since all research used to develop such therapies starts with the artificial creation of human embryos, most of which are then destroyed, “it must be stated that, in its current state, germ-line cell therapy in all its forms is morally illicit.”

Much of the objection to the proposal comes from the fact that alterations to mitochondrial DNA (mtDNA) result in genetic changes that will be carried down the line of inheritance when the embryo becomes an adult and has his or her own children.

This “germ-line” genetic therapy was condemned by the 2008 CDF document, which said when “genetic modifications are effected on the germ cells of a person will be transmitted to any potential offspring,” the procedure cannot be morally licit.

The ethics of the procedure are not the only concerns. The Scientist also reports that some clinical “safety” issues remain unresolved. The researchers who developed the technique reported genetic abnormalities in about half the embryos created, and other researchers have expressed concerns “about the compatibility of the mitochondrial and nuclear DNA from two different donors.”

Most of the research community is dismissive of such concerns. In 2012, Sir Mark Walport, then head of the UK’s Wellcome Trust, described mitochondrial gene transfer as merely the equivalent of “changing the batteries in a camera.” The trust had just awarded a grant of £5.8 million to researchers at Newcastle University, a major center for embryo research.

The procedure was described in an article in The Scientist as a means of avoiding the various pathologies caused by genetic anomalies in the mitochondria, the tiny organelles found in the cytoplasm that act as “batteries” providing power to an organism’s cells.

In it, the nucleus from the ovum of a woman carrying “mitochondrial defects” is transferred into the second “donor egg,” whose cytoplasm is free of the mitochondrial defects and from which the nucleus has been removed.

The result is an ovum, (oocyte or female gamete) that has the nuclear DNA of the first woman, but with the defect-free cytoplasm of the second woman. The resulting genetically modified ovum is then fertilized with the sperm, becoming an embryo which can be implanted in the “donor” who has the mitochondrial disorder.

The technique was developed by a team of biologists at Oregon Health and Science University in Beaverton in 2009, which created healthy rhesus monkeys free of mitochondrial genetic disorders. In 2012, the same team announced success in human trials, having created a dozen human embryos, all of which were later “destroyed,” who had no mitochondrial disorders.

Those with concerns may contact the FDA:

Gail Dapolito

Phone: 301-827-1289,

Fax: 301-827-0294

e-mail: [email protected]

Writers are asked to use “Cellular, Tissue and Gene Therapies Advisory Committee Meeting Comment” as the e-mail’s subject line.

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Indiana Gov. Mike Pence signs the state's Religious Freedom Restoration Act.
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Indiana faces backlash as it becomes 20th state to protect religious liberty

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By Ben Johnson

INDIANAPOLIS, IN, March 27, 2015 (LifeSiteNews.com) – On Thursday, Indiana became the 20th state to prevent the government from forcing people of faith to violate their religious beliefs in business or the public square.

Gov. Mike Pence signed the Religious Freedom Restoration Act (SB 101) into law, saying the freedom of religion is a preeminent American value.

“The Constitution of the United States and the Indiana Constitution both provide strong recognition of the freedom of religion, but today, many people of faith feel their religious liberty is under attack by government action,” Pence said.

Gov. Pence, a possible dark horse candidate for president in 2016, cited court cases brought by religious organizations and employers, including Catholic universities, against the HHS mandate. “One need look no further than the recent litigation concerning the Affordable Care Act. A private business and our own University of Notre Dame had to file lawsuits challenging provisions that required them to offer insurance coverage in violation of their religious views.”

The new law could also prevent Christian business owners from being compelled to bake a cake or take photographs of a same-sex "marriage" ceremony, if doing so violates their faith. In recent years, business owners have seen an increased level of prosecution for denying such services, despite their religious and moral beliefs.

The state's pro-life organization applauded Pence for his stance. "Indiana's pro-life community is grateful to Gov. Mike Pence for signing the Religious Freedom Restoration Act into law,” said Indiana Right to Life's president and CEO Mike Fichter. “This bill will give pro-lifers a necessary legal recourse if they are pressured to support abortion against their deeply-held religious beliefs.”

“RFRA is an important bill to protect the religious freedom of Hoosiers who believe the right to life comes from God, not government,” he said.

The state RFRA is based on the federal bill introduced by Sen. Chuck Schumer, D-NY, and signed into law by President Bill Clinton in 1993. The Supreme Court cited the federal law when it ruled that Hobby Lobby had the right to refuse to fund abortion-inducing drugs, if doing so violated its owners' sincerely held religious beliefs.

In signing the measure – similar to the one Arizona Gov. Jan Brewer vetoed – Pence and the state of Indiana have faced a torrent of venom from opponents of the bill, who claim it grants a “right to discriminate” and raises the spectre of segregation.

"They've basically said, as long as your religion tells you to, it's OK to discriminate against people," said Sarah Warbelow, legal director of the Human Rights Campaign, a national homosexual pressure group.

The Disciples of Christ, a liberal Protestant denomination based in the state capital, has said it will move its 2017 annual convention if the RFRA became state law. The NCAA warned the bill's adoption “might affect future events” in the Hoosier state.

Pence denied such concerns, saying, "This bill is not about discrimination, and if I thought it legalized discrimination in any way I would've vetoed it."

The bill's supporters say that, under the Obama administration, it is Christians who are most likely to suffer discrimination.

"Originally RFRA laws were intended to protect small religious groups from undue burdens on practicing their faith in public life,” said Mark Tooley, president of the Institute on Religion and Democracy. “It was not imagined there would come a day when laws might seek to jail or financially destroy nuns, rabbis or Christian camp counselors who prefer to abstain from the next wave of sexual and gender experimentation. And there's always a next wave.”

The bill's supporters note that it does not end the government's right to coerce people of faith into violating their conscience in every situation. However, it requires that doing so has to serve a compelling government interest and the government must use the least restrictive means possible. “There will be times when a state or federal government can show it has a compelling reason for burdening religious expression – to ensure public safety, for instance,” said Sarah Torre, an expert at the Heritage Foundation. “But Religious Freedom Restoration Acts set a high bar for the government to meet in order to restrict religious freedom.”

Restricting the ability of government to interfere in people's private decisions, especially their religious decisions, is the very purpose of the Constitution, its supporters say.

"Religious freedom is the cornerstone of all liberty for all people,” Tooley said. “Deny or reduce it, and there are no ultimate limits on the state's power to coerce."

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Fight pornography. Beat pornography. And join the ranks of those who support their fellow men and women still fighting.
Jonathon van Maren Jonathon van Maren Follow Jonathon

Porn is transforming our men from protectors into predators. Fight back.

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By Jonathon van Maren

Since I’ve gotten involved in anti-pornography work, I’ve met countless men who struggle, fight, or have beaten pornography. Each person seems to deal with the guilt and shame that accompanies porn use in a different way—some deny that it’s “all that bad,” others pretend that they could “stop whenever they want,” many insist that “everyone is doing it,” and most, when pressed, admit to a deep sense of self-loathing.

One worry surfaces often in conversation: What do my past or current struggles with pornography say about me as a man? Can I ever move past this and have a meaningful and fulfilling relationship?

I want to address this question just briefly, since I’ve encountered it so many times.

First, however, I’ve written before how I at times dislike the language of “struggling” with pornography or pornography “addiction,” not because they aren’t accurate but because too often they are used as an excuse rather than an explanation. It is true, many do in fact “struggle” with what can legitimately be considered an addiction, but when this language is used to describe an interminable battle with no end (and I’ve met dozens of men for whom this is the case), then I prefer we use terminology like “fighting my porn habit.” A semantic debate, certainly, but one I think is important. We need to stop struggling with porn and start fighting it.

Secondly, pornography does do devastating things to one’s sense of masculinity. We know this. Pornography enslaves men by the millions, perverting their role as protector and defender of the more vulnerable and turning them into sexual cannibals, consuming those they see on-screen to satisfy their sexual appetites.

What often starts as mere curiosity or an accidental encounter can turn into something that invades the mind and twists even the most basic attractions. I’ve met porn users who can’t believe the types of things they want to watch. They haven’t simply been using porn. Porn has actively reshaped them into something they don’t recognize and don’t like. 

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Porn is this generation’s great assault on masculinity and the role of men in society. It is essential that we win this battle for the sake of society’s survival. Contrary to what the gender-bending and family-morphing progressive elites claim, good husbands and good fathers and good church leaders are necessary for a healthy society. But pornography is destroying marriages, creating distant and disconnected fathers, and, metaphoricaclly castrating men, hindering their ability and desire to make a positive difference in the society around us.

So, with this sobering set of facts in mind let’s return to the question: what do pornography struggles, past and present, say about a man?

The proper way to respond is with everything that is good about masculinity. We have to fight pornography as men have fought countless evils throughout the ages. We need to fight pornography to protect women, and wives, and children, and our society at large. This is how pornography threatens society, by castrating men, and turning them from protectors into predators. Rooting out the evil in our own lives allows us to better fulfill the role we are called to perform in the lives of others. Battling our own demons enables us to battle the wider cultural demons. Every day without porn is another bit of virtue built. Virtue is not something you’re born with. Virtues are habits that you build. And one day without porn is the first step towards the virtue of being porn-free.

Many men ask me if men who have had past porn addictions are cut out for being in a relationship or working in the pro-life movement or in other areas where we are called to protect and defend the weak and vulnerable. And the answer to that is an unequivocal yes. Our society needs men who know what it means to fight battles and win. Our society needs men who can say that they fought porn and they beat porn, because their families and their friends were too important to risk. Our society needs men who rose to the challenge that the evils of their generation threw at them, and became better men as the result. And our society needs men who can help their friends and their sons and those around them fight the plague of pornography and free themselves from it, too—and who can understand better and offer encouragement more relevant than someone who has fought and been freed themselves?

So the answer to men is yes. Fight pornography. Beat pornography. And join the ranks of those who support their fellow men and women still fighting. Lend them support and encouragement. We cannot change the fact that porn has left an enormous path of destruction in its wake. But we can change the fact that too many people aren’t fighting it. We can change our own involvement. And we can rise to the challenge and face this threat to masculinity with all that is good about masculinity.

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Red Alert!

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By John-Henry Westen

I don’t like having to do this, but we have always found it best to be totally upfront with our readers: our Spring fundraising campaign is now worrying us! 

You see, with just 6 days remaining, we have only raised 30% of our goal, with $125,000 still left to raise. That is a long ways to go yet.

We have no choice but to reach our minimum goal of $175,000 if we are going to be able to continue serving the 5+ million readers who rely on us every month for investigative and groundbreaking news reports on life, faith and family issues.

Every year, LifeSite readership continues to grow by leaps and bounds. This year, we are again experiencing record-breaking interest, with over 6 million people visiting our website last month alone!

This unprecedented growth in turn creates its own demand for increased staff and resources, as we struggle to serve these millions of new readers.

And especially keep this in mind. As many more people read LifeSite, our mission of bringing about cultural change gets boosted. Our ultimate goal has always been to educate and activate the public to take well-informed, needed actions.

Another upside to our huge growth in readers is that it should be that much easier to reach our goal. To put it simply: if each person who read this one email donated whatever they could (even just $10) we would easily surpass our goal! 

Today, I hope you will join the many heroes who keep this ship afloat, and enable us to proclaim the truth through our reporting to tens of millions of people every year!

Your donations to LifeSite cause major things to happen! We see that every day and it is very exciting. Please join with us in making a cultural impact with a donation of ANY AMOUNT right now. 

You can also donate by phone or mail. We would love to hear from you!

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