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COVID-19 injectionChildren's Health Defense

(LifeSiteNews) — Doctors  Vanden Bossche and Montagnier have warned us about vaccinating during a pandemic with heavy infectious pressure and the use of very narrow spike specific (an immature, sub-optimal, incomplete, immune library spectrum) yielding sub-optimal antibodies and possibly driving vaccine-mediated viral immune escape.  I argue we are seeing just that now in the UK, Israel, and even the U.S. “It is clear that the new variants are created by antibody-mediated selection due to the vaccination,” Montagnier said. It is the vaccination and sub-optimal incomplete “unhinged and deranged” antibody responses that are driving the emergence of the variants. Is this why so many young healthy athletes are dying?`

It is now abundantly clear that the COVID-19 vaccines are ‘leaky’ (leaky vaccines do not stop infection or transmission and allow for immune escape) and do not sterilize the COVID virus. Either they are non-neutralizing, or they lose the neutralizing capacity very quickly. These vaccines show that the more vaccinated a nation is, the more problems it has with the vaccine in terms of escalating infections. These vaccines do not adequately protect the upper respiratory tract. The data is clear that the vaccinated can transmit the virus as efficiently as some people who are completely unprotected. Immunity from the vaccines seems to last only about 4 to 5 months, and thus how could anyone think we can achieve population level herd immunity with these vaccines? It is virtually impossible that these vaccines could get us to herd immunity. There is a zero chance. Yet are we about to accept boosting every 5 months? Do we know if the immune system is designed for this? This, as well as antibody dependent enhancement (ADE) and antibody mediated viral enhancement (AMVE), was not studied. This was a catastrophic omission and failure by the vaccine developers and the FDA as the key regulator in enforcing this.

Yet why would the CDC, NIH, vaccine developers, and their supporters continue to push these leaky, imperfect vaccines onto the population, especially onto low-risk persons, when the antibody immunity quickly wanes? All they did was set the population up for repeated boosters that also carry risk. Why did vaccine developers roll out these imperfect vaccines if they were set to fail from the start? As mentioned, we have not studied if the human immune system is capable of withstanding repeat vaccine boosting. We are seeing that the vaccinated are, at some point, driving transmission with a vaccine that has limited and questionable immunity.

My thesis is that the double-vaccinated and triple-vaccinated (likely quadruple vaccinated in Israel) are driving the transmission of the Delta variant and that this has severe consequences for the vulnerable unvaccinated and the vaccinated, too. They are potentially functioning as asymptomatic super spreaders. I suggest that these COVID vaccines are keeping the vaccinated person alive but allowing for infection and transmission which could permit very virulent strains to circulate within a population. What we are seeing at present cannot really be explained by differences in variants and this breakdown in infections among vaccinated persons. People who are double vaccinated are being made to shed virus at alarmingly high levels.

The Marek’s disease (Read et al.) in chickens model (in which ‘leaky’ non-sterilizing, non-neutralizing imperfect vaccines reduce symptoms but do not stop infection or transmission) and the concept of the Original antigenic sin (in which the initial priming or exposure of the immune system prejudices the immune response life-long to that pathogen/virus or similar ones, and if the initial priming of the immune system is indeed sub-optimal, then the subsequent response [exposure] may be sub-optimal to that pathogen or similar/related ones) may explain what we are potentially facing now with these imperfect COVID vaccines: immune escape, increased viral load, increased transmission, faster transmission, and potentially “hotter” variants.

I wish to make the case that we may be able to explain the surging infections, hospitalizations and death in vaccinated persons as well as unvaccinated persons via the concept of the Original antigenic sin. While some may argue that it is a theoretical argument, the data I am seeing could well be explained by it. I see no other explanation right now for what we are seeing in the post-vaccine data in the U.K., Israel, the U.S., and other places.

Penn State’s Ohm writes, “Leaky vaccines work…without necessarily blocking or slowing viral replication. The result is that infected but vaccinated individuals have extended survival, allowing   highly virulent pathogen that would normally reach an evolutionary dead-end in a dead host, can transmit.” Boots echoed this, and again we suggest that we are possibly facing a Marek 2.0 now with these clearly imperfect COVID vaccines. Yes, more data and acute definitive research is needed, for this was not studied by the vaccine developers. Moreover, we are in the dark as to how safely these vaccines behave in the medium- and long-term. We are in a black box situation. However, what is shaping up raises many urgent questions and is potentially ominous. We run the risk of killing many people, particularly our children, with these vaccines if what we are seeing is the tip of ADE/AMVE.

We are seeing major COVID hospitalizations, ICU admissions, and deaths in the U.K. among the fully vaccinated. This is a huge problem, and this may be an AMVE/ADE that we feared. It is a virologist’s worst nightmare. An enhancing antibody need not be present (as said Dr. Dan Stock, in a personal communication on November 8, 2021), and this nuance must be factored into our discussion. “The greatest deficit is that caused by Th 2 shifting away from CD 8+ cytotoxic natural killer cellular response to the local infection, which is necessarily induced, regardless of what type of Ab gets produced…unhelpful antibodies really are not required for the immune system derangement.”

I argue that the corners cut in the vaccine trials and manufacture under Operation Warp Speed (OWS), in order to reduce the timelines, may have resulted in sub-optimal harmful vaccines being brought to society. Was President Trump misled and misinformed by his scientific advisors and vaccine developers? I argue that they did mislead him. Had the studies been conducted properly regarding vaccine safety and according to the proper durations,  and had we followed up long enough to examine AMVE/ADE, then it is likely that we would not be witnessing what is unfolding in the British data and the Israeli data today. Nor would we see in the U.S. the clear vaccine failure and the potentially dangerous need for repeat boosting. Repeat boosting could be devastating.

I write here because of my fear of what might happen if we proceed to mass-vaccinate healthy children. Based on what has materialized thus far, we think many children could be seriously hurt with these vaccines. Importantly, children just do not have a significant risk from the COVID-19 virus and must be left alone. This vaccine is not needed, and neither the government public health leaders (Francis Collins/NIH, Anthony Fauci/NIAID, Rochelle Walensky/CDC, Woodcock and Marks/FDA), nor vaccine developers have presented their case for why children need these vaccines. Moreover, we run the risk of turning children into asymptomatic super spreaders (as is happening in adults now in the U.K., Israel, and the U.S., as well as incurring lethal outcomes if we move forward with mass vaccination.

Where is the evidence that underpins my thesis that we are indeed staring down the barrel of Marek 2.0? The recent Public Health England (PHE) reports # 44 and # 45 are a key aspect of this thesis (as are 5 prior PHE reports) and, while speculative and theoretical, I think these reports raise serious issues that I cannot dismiss. I think I have even gone past the theoretical. I will unfold the discussion with the following studies that set the table by revealing the failure and immense challenges with the current vaccines (particularly Pfizer) with regard to the Delta variant.

The vaccine’s failure against the Delta variant

The vaccine has clearly failed against Delta, and the fully vaccinated are revealing staggering infection and propensity to transmit. For example, we have at present research findings by Singanayagam et al. that fully vaccinated individuals with breakthrough infections have peak viral loads similar to unvaccinated cases and can efficiently transmit infection in household settings, including to fully vaccinated contacts. We have findings by Chau et al. that viral loads of breakthrough Delta variant infection cases in vaccinated nurses were 251 times higher than those of cases infected with prior strains early 2020. We have findings by Riemersma et al. that there is no difference in viral loads when comparing unvaccinated individuals to those who have vaccine “breakthrough” infections, and that if vaccinated individuals become infected with the Delta variant, they may be sources of SARS-CoV-2 transmission to others. These findings all reveal that the vaccines have very sub-optimal efficacy.

This troubling situation of the vaccinated being highly infectious and transmitting the virus has also clearly emerged in seminal nosocomial outbreak papers by Chau et al. (about healthcare workers [HCWs] in Vietnam), the Finland hospital outbreak (a spread among HCWs and patients), and the Israel hospital outbreak (a spread among HCWs and patients). These studies also troublingly revealed that the PPE and masking were essentially ineffective within the healthcare setting. All of the HCWs were double vaccinated, and yet there was extensive spread to themselves and their patients.

In addition, Nordström et al. found that the vaccine effectiveness of Pfizer against infection waned progressively from 92% on day 15-30 to 47% by day 121-180, and that from day 211 and onwards it had no effectiveness.

Suthar et al. found a substantial waning of antibody responses and T cell immunity to SARS-CoV-2 and its variants, at 6 months following the second immunization.

Yahi et al. discovered that, with the Delta variant, neutralizing antibodies have a decreased affinity for the spike protein, whereas facilitating antibodies display a strikingly increased affinity.

Juthani et al. found a higher number of patients with severe illness, or critical illness, in those who received the Pfizer vaccine.

Gazit et al. discovered that SARS-CoV-2-naïve vaccinees had a 13-fold increased risk for breakthrough infection with the Delta variant, and a substantially elevated risk of symptomatic COVID and hospitalization.

Acharya et al. found no significant difference in cycle threshold values between vaccinated and unvaccinated, asymptomatic and symptomatic groups infected with Delta.

Levine-Tiefenbrun et al. report that the viral load reduction effectiveness declines with time after vaccination, “significantly decreasing at 3 months after vaccination and effectively vanishing after about 6 months.”

These findings collectively reveal the poor efficacy and even negative efficacy of the COVID vaccines.

As an example, this Swedish study (retrospective with 842,974 pairs (N=1,684,958)) is particularly alarming, for it shows that while the vaccine provides temporary protection against infection, the efficacy declines below zero and then to negative efficacy territory at approximately 7 months. This underscores that the vaccinated are highly susceptible to infection and eventually become highly infected, more so than the unvaccinated.

A further example emerges from Ireland, where reporting suggests that Waterford city district has the nation’s highest rate of Covid-19 infections, while the county also boasts the highest rate of vaccination in the Republic: 99.7% are vaccinated.

There are reports that the U.S. Covid-19 deaths for 2021 surpassed the deaths from 2020, leading some to state that “more people have died from COVID-19 in 2021, with most adults vaccinated and nearly all seniors, than in 2020 when nobody was vaccinated.”

Therefore, the evidence has accumulated that there are breakthrough infections, and the vaccine is failing against the Delta variant. There is no doubt. Even CDC’s Director Rochelle Walensky admitted that the vaccines are not stopping transmission, an admission of a failed vaccine. Again, the Marek’s disease in chickens and the vaccination situation explains what we are potentially facing with these leaky vaccines: increased transmission, faster transmission, and ‘hotter’ variants.

One model of AMVE/ADE surrounds the Original antigenic sin and the initial priming of the immune system or exposure, prejudicing the immune response life-long to that pathogen/virus or similar. Moreover, if the initial priming of the immune system is indeed sub-optimal, then the subsequent response (exposure) may be sub-optimal to that pathogen or similar/related ones.

I am conscious that I am not a virologist or immunologist as I seek to make sense of the data we are seeing and what is happening to vaccinated and unvaccinated persons. I am guided by the tremendous work of Dr. Dan Stock, and my explanation of the post vaccination situation (with his expert input) is as follows:

If the initial priming/exposure is via vaccine, then the helper T-cell (CD 4+) immune response would be biased (switched) toward a Th 2 B-cell and antibody response and a more limited Th1 CD 8+ cytotoxic T cell response at the localized native site of infection. The immune system is forced to choose between Th 1 and Th2 differentiation, and that such differentiation is permanent.  It is “learning” that anytime you are exposed to the virus (or similar virus) in the wild, it should switch to the Th 2 pathway and make less Th 1 cytotoxic immunity because you have taken the vaccine. The immune system is forced to switch between Th 1 and Th 2 immune responding pathways, and if it does respond systemically with antibodies (if your first exposure is vaccine), then when you are indeed infected in the future with the virus as a localized respiratory tract infection (i.e. your immune system’s second look at the virus), your immune system (disturbed) would be responding wrong  and not with the cytotoxic CD 8+ response that is actually (and optimally) needed at the site of infection (i.e. the respiratory tract). In other words, the signals sent by the local tissue to the immune system says to produce B cells and antibodies and not the cytotoxic cells needed at the local site of infection to begin clearing the infection out.

The result is that the respiratory tissue (lungs) become more infected because the cytotoxic cells are not there or because not enough of them are produced to clear the infection. The tissue becomes and sicker and sicker, and the infected person could become very infected with more and more virus as the CD 8+ response is diminished or perhaps even non-existent. The vaccinated person would then become potentially very ill and, at the same time, amass a large viral load and become capable of transmitting the virus. So, the infection is building up in the local tissues (the primary site of infection) and not being cleared by the cytotoxic response which has been tamped down.

This may help explain the data we are seeing out of the U.K. (reports # 44 & 45 and reports 39-43) with deaths not only in the vulnerable unvaccinated but in the vaccinated, too. This is a real problem if this is indeed what is occurring. A systemic presentation (due to the vaccine) must necessarily reduce Th 1 response as it drives Th 2 response, allowing not only increased shedding, but eventually driving a pathogen that would normally not rapidly disseminate, and certainly not before it was eradicated, into an uncheckable pathogen that would more rapidly and dependably disseminate, further driving progressive Th 2 differentiation, reduced Th 1 response, until eventually the infection would not have any meaningful Th 1 response.

The result is the lungs are destroyed and the upper limit of Th 2 response is reached. Then we would see not only spread to the naive unvaccinated, but increased death in the vaccinated, who would never recover with proper immune response as the immune system ‘learns’ the initial sub-optimal incorrect response (moving away from CD 8+ cytotoxic responding) and responds in that direction with subsequent exposure/boosting.

Boosting will be devastating for it will only drive this deranged immune response, and it will build and the vaccinated will get sicker and sicker for there is no Th 1 cytotoxic response available. The immune system effectively learns to respond incorrectly, and the result is the tissue in the respiratory tract/lungs getting sicker and more and more infected and sicker. The vaccinated person is as much at risk of severe illness as the vulnerable unvaccinated is at risk of infection and a severe outcome. Even if the nearby unvaccinated person has a robust immune system, it could be overwhelmed with virus from the vaccinated person who is shedding and churning out massive infection as the CD 8+ pathways are stepped down. Both can become very ill and die.

So when we look more closely at the Public Health England (PHE) report # 44 & 45 (and reports # 39 to 43), which has very granular data, we see that the infections are markedly higher in those vaccinated in all age groups over 30 (tables 2-5), the shift to those 30 years and above occurring between week 35 and week 38 in the report # 39. Table 5, while reporting unadjusted data, is very instructive regarding the most current rates between week 40 and week 43 2021 (page 20 in report # 44) (Table 1 & 2), and note week 44 data is reported as ‘unadjusted’. The same emerges in report # 45 (Table 6 page 22, between week 41 and week 44 2021).

We see a stable and consistent trend in this robustly collected and reported U.K. data in that the vaccinated (it appears) are becoming more highly infected with the Delta variant and the unvaccinated are being hospitalized and dying alongside the vaccinated.

The unvaccinated are a particular concern given their vulnerability and these alarming rates. A recent Yahoo UK report and others are sounding the alarm that we are witnessing the highest rates of infection, hospitalization, and death in the nations most vaccinated. There are similar reports in Scotland that the fully vaccinated accounted for “89% of Covid-19 deaths in the past four weeks, whilst also accounting for 77% of Covid-19 hospitalisations and 65% of alleged Covid-19 cases from October 9th through to November 5th.”

Conclusion

Is the COVID vaccine protecting us from serious damage while not preventing us from getting the virus, and therefore (as seen in the UK data) driving more lethal variants? Are we really looking at an imperfect vaccination that keeps us alive but allows the transmission, and not the killing, of the virus, so that the vaccinated are transmitting an actually more potent virus? Are the vaccinated themselves are becoming very ill given a deranged immune response? As seen in the vaccination against Marek’s disease in chickens, we may be witnessing that vaccination against the COVID-19 virus and disease is favouring higher virulence in both the vaccinated and the vulnerable unvaccinated.

From where I sit, I argue that this is not a theoretical risk anymore and the data we are looking at suggests this is actually what we are witnessing now in Israel, the U.K., and other places. I see no other data that could explain what we are witnessing, and this deranged, incorrect immune response between switch Th 1 to Th 2 immune responding seems to be the best explanation thus far.

How do we address this, as this is potentially catastrophic? I argue for a stop to the vaccination (or to focus on high-risk persons if they are properly informed and consented; we should offer, or make available the vaccine, but we should not mandate it) and the reality is that, if this model bears out,  boosting will further derange the immune system—make it biased toward an antibody response and thus the cytotoxic immune response needed upon subsequent exposures will not be there or will be severely set aside.

I also say, under no condition, none, do we allow our low-risk healthy children to be vaccinated with these sub-optimal, imperfect, leaky and largely safety-untested vaccines that provide them only a potential opportunity for harm. My view is we impose a hard stop now on these vaccines/boosters. We must ask the vaccine developers to address the harms we are seeing before moving further and, in fact, we have many alternatives to address this emergency. We do not need these vaccines. We never did. It is imperative to consider alternatives beyond just vaccinating, e.g. using non-vaccine disease prevention, such as early outpatient treatment and such available nutraceuticals as Vitamin D/calcifediol, zinc, and prophylactic ivermectin.

 

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